Could CDK4/6 inhibitors be a standard of care for advanced breast cancer?

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CDK4/6 inhibitor clinical trials in advanced breast cancer

The cyclin-dependent kinase 4 and 6 inhibitors (CDK4/6 inhibitors) abemaciclib, palbociclib, and ribociclib have been approved by the FDA and the EMA for the treatment of hormone receptor-positive (HR+) and human epidermal growth factor receptor 2 negative (HER2-) advanced breast cancer (ABC).

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